Aly(OH)3y-zClz·nH2O·mC3H8O2
Al2(H2O)y-z(OH)6-n(Cl)n(C3H8O2)z
Aluminum chlorohydroxide, hydrate: propylene glycol complex (1:1).
Aluminum hydroxychloride, hydrate: propylene glycol complex (1:1)
[
53026-85-0].
Packaging and storage—
Preserve in well-closed containers.
Labeling—
The label states the content of anhydrous aluminum chlorohydrate.
Identification—
A:
A solution (1 in 10) responds to the tests for
Aluminum 
191
and for
Chloride 191.
Test specimen—
Dissolve 0.5 g in about 40 mL of water, and while mixing adjust with 2.5 N sodium hydroxide to a pH of 9.55 ± 0.05. Filter the suspension of precipitate thus obtained. Evaporate about 15 mL of the filtrate to about 1 mL on a hot plate. Deposit this solution on a silver chloride disk.
Standard specimen:
a similar preparation of propylene glycol.
pH 791:
between 3.0 and 5.0, in a solution [15 in 100 (w/w)].
Limit of iron—
Using Aluminum Chlorohydrex Propylene Glycol instead of Aluminum Chlorohydrate, proceed as directed in the test for
Limit of iron under
Aluminum Chlorohydrate. The limit is 150 µg per g.
Content of aluminum—
Edetate disodium titrant—
Prepare and standardize as directed in the
Assay under
Ammonium Alum, except to use 37.2 g of edetate disodium instead of 18.6 g.
Test solution—
Transfer about 1.6 g of Aluminum Chlorohydrex Propylene Glycol, accurately weighed, to a 100-mL beaker, add 15 to 20 mL of water and 5 to 6 mL of hydrochloric acid, and boil on a hot plate for 15 to 20 minutes. Cool the solution, and with the aid of water transfer to a 100-mL volumetric flask. Dilute with water to volume, and mix.
Procedure—
Transfer 5.0 mL of the
Test solution to a 250-mL beaker, add 10 to 15 mL of water, and adjust with 1 N sodium hydroxide to a pH of 1.5 ± 0.5. Add 10.0 mL of
Edetate disodium titrant, and heat to boiling. Cool the solution and carefully introduce a magnetic stirring bar into the beaker. Add 10 to 15 mL of acetic acid–ammonium acetate buffer TS, 40 to 50 mL of alcohol, and while stirring adjust with glacial acetic acid to a pH of 4.6 ± 0.1. Add 1 to 2 mL of dithizone TS and 40 to 50 mL of alcohol, and titrate with 0.1
M zinc sulfate VS until the color changes from a green-violet to a rose-pink. Perform a blank titration, and make any necessary correction. Each mL of 0.1 M
Edetate disodium titrant consumed is equivalent to 2.698 mg of aluminum (Al). Use the aluminum content thus obtained to calculate the
Aluminum/chloride atomic ratio.
Aluminum/chloride atomic ratio—
Divide the percentage of aluminum found in the
Assay by the percentage of chloride found in the test for
Content of chloride, and multiply by 35.453/26.98, in which 35.453 and 26.98 are the atomic weights of chlorine and aluminum, respectively: the ratio is between 1.91:1 and 2.1:1.
Assay—
Calculate the percentage of anhydrous aluminum chlorohydrate in the Aluminum Chlorohydrex Propylene Glycol by the formula:
Al({26.98
x + [17.01(3
x 
1)] + 35.453} / 26.98
x),
in which
Al is the percentage of aluminum found in the test for
Content of aluminum,
x is the aluminum/chloride atomic ratio, 26.98 is the atomic weight of aluminum, 17.01 is the molecular weight of the hydroxide ion (OH), and 35.453 is the atomic weight of chlorine (Cl).
