Procedure
Determine the amount of cefprozil (C
18H
19N
3O
5S) dissolved in the
Dissolution Medium, as directed in the
Assay, using instead of the
Assay preparation a filtered portion of the
Dissolution Medium, diluted if necessary, to obtain a test solution containing about 0.3 mg of cefprozil per mL. Calculate the quantity, in mg, of cefprozil (
Z)-isomer and cefprozil (
E)-isomer dissolved by the formula:
0.9(CPD)(rU / rS),
in which
D is 1 or, where the filtered
Dissolution Medium was diluted to prepare the test solution, the appropriate dilution factor, and the other terms are as defined therein. Calculate the quantity, in mg, of cefprozil (C
18H
19N
3O
5S) dissolved by adding the quantity, in mg, of the cefprozil (
Z)-isomer and cefprozil (
E)-isomer dissolved.