U.S. PHARMACOPEIA

Search USP29  
Testosterone Propionate
C22H32O3 344.49

Androst-4-en-3-one, 17-(1-oxopropoxy)-, (17)-.
Testosterone propionate [57-85-2].
» Testosterone Propionate contains not less than 97.0 percent and not more than 103.0 percent of C22H32O3, calculated on the dried basis.
Packaging and storage— Preserve in well-closed, light-resistant containers.
Identification—
Solution: 10 µg per mL.
Medium: alcohol.
Absorptivities at 241 nm, calculated on the dried basis, do not differ by more than 3.0%.
C: It responds to Identification test C under Testosterone Enanthate.
Melting range 741: between 118 and 123.
Specific rotation 781S: between +83 and +90.
Test solution: 20 mg, previously dried, per mL, in dioxane.
Loss on drying 731— Dry it in vacuum over silica gel for 4 hours: it loses not more than 0.5% of its weight.
Organic volatile impurities, Method IV 467: meets the requirements.
Residual solvents 467: meets the requirements.
(Official January 1, 2007)
Assay— Proceed with Testosterone Propionate as directed in the Assay under Testosterone Enanthate, except to use USP Testosterone Propionate RS and otherwise substitute Testosterone Propionate throughout. Calculate the quantity, in mg, of C22H32O3 in the Testosterone Propionate taken by the formula given therein.
Auxiliary Information— Staff Liaison : Daniel K. Bempong, Ph.D., Scientist
Expert Committee : (MDPS05) Monograph Development-Pulmonary and Steroids
USP29–NF24 Page 2090
Phone Number : 1-301-816-8143