Packaging and storage
Preserve in well-closed containers.
Identification
Solution:
15 µg per mL.
Medium:
water.
C:
A solution (1 in 100) responds to the tests for
Chloride 191.
pH 791:
between 5.0 and 6.0, in a solution (1 in 100).
Ordinary impurities 466
Test solution:
methanol.
Standard solution:
methanol.
Eluant:
a mixture of chloroform, cyclohexane, and diethylamine (5:4:1).
Visualization:
12.
Assay
Dissolve about 250 mg of Benoxinate Hydrochloride, accurately weighed, in a mixture of 20 mL of glacial acetic acid and 20 mL of acetic anhydride, and titrate with 0.1 N perchloric acid VS, determining the endpoint potentiometrically. Perform a blank determination, and make any necessary correction. Each mL of 0.1 N perchloric acid is equivalent to 34.49 mg of C17H28N2O3·HCl.