Identification
A:
It meets the requirements of the flame test for
Potassium 191.
B:
Evaporate 5 mL on a steam bath to dryness: a mineral oil dispersion of the residue exhibits an IR absorption maximum in the spectral region between 6.2 and 6.25 µm (carboxylic acid salt).
Assay
Potassium stock solution and Standard preparations
Prepare as directed in the
Assay under
Potassium Gluconate.
Assay preparation
Transfer an accurately measured volume of Oral Solution, equivalent to about 1.8 g of potassium gluconate, to a 1000-mL volumetric flask, dilute with water to volume, and mix. Transfer 10.0 mL of the solution to a 100-mL volumetric flask, dilute with water to volume, and mix. Transfer 5.0 mL of the resulting solution to a 100-mL volumetric flask, add 2.0 mL of sodium chloride solution (1 in 5) and 1.0 mL of hydrochloric acid, dilute with water to volume, and mix.
Procedure
Proceed as directed for
Procedure in the
Assay under
Potassium Gluconate. Calculate the quantity, in mg, of potassium gluconate (C
6H
11KO
7) in each mL of the Oral Solution taken by the formula:
(200C / V)(234.25 / 39.10),
in which
V is the volume of Oral Solution taken; 234.25 is the molecular weight of potassium gluconate; and 39.10 is the atomic weight of potassium.