C6H14O2 118.17

2,4-Pentanediol, 2-methyl-, (±)-.
(±)-2-Methyl-2,4-pentanediol [107-41-5].

Packaging and storage— Preserve in tight containers.

USP Reference standards 11— USP Hexylene Glycol RS.

Identification, Infrared Absorption 197F, on undried specimen.

Specific gravity 841: between 0.917 and 0.923.

Refractive index 831: between 1.424 and 1.430.

Acidity— Mix 1 mL of phenolphthalein TS with 50 mL of water, and add 0.1 N sodium hydroxide until the solution remains pink for 30 seconds. Add 10 mL of Hexylene Glycol, accurately measured, and titrate with 0.10 N sodium hydroxide until the original pink color returns and remains for 30 seconds: not more than 0.20 mL of 0.10 N sodium hydroxide is required.

Water, Method I 921: not more than 0.5%.

Residual solvents 467: meets the requirements.

Expert Committee : (EM105) Excipient Monographs 1

USP29–NF24 Page 3345

Phone Number : 1-301-816-8262