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Eugenol
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C10H12O2 164.20

Phenol, 2-methoxy-4-(2-propenyl)-.
4-Allyl-2-methoxyphenol [97-53-0].
» Eugenol is obtained from Clove Oil and from other sources.
Packaging and storage— Preserve in tight, light-resistant containers.
Solubility in 70 percent alcohol— One volume dissolves in 2 volumes of 70 percent alcohol.
Specific gravity 841: between 1.064 and 1.070.
Distilling range, Method II 721 Not less than 95% distils between 250 and 255.
Refractive index 831: between 1.540 and 1.542 at 20.
Heavy metals, Method II 231: 0.004%.
Hydrocarbons— Dissolve 1 mL in 20 mL of 0.5 N sodium hydroxide in a stoppered, 50-mL tube, add 18 mL of water, and mix: a clear mixture results immediately, but it may become turbid when exposed to air.
Limit of phenol— Shake 1 mL with 20 mL of water, filter, and add 1 drop of ferric chloride TS to 5 mL of the clear filtrate: the mixture exhibits a transient grayish green color but not a blue or violet color.
Residual solvents 467: meets the requirements.
(Official January 1, 2007)
Auxiliary Information— Staff Liaison : Clydewyn M. Anthony, Ph.D., Scientist
Expert Committee : (MDCCA05) Monograph Development-Cough Cold and Analgesics
USP29–NF24 Page 881
Phone Number : 1-301-816-8139