U.S. PHARMACOPEIA

Search USP29  
Cascara Sagrada Fluidextract
» Prepare Cascara Sagrada Fluidextract as follows. To 1000 g of coarsely ground Cascara Sagrada add 3000 mL of boiling water, mix, and allow to macerate in a suitable percolator for 2 hours. Allow the percolation to proceed at a moderate rate, gradually adding boiling water until the drug is practically exhausted of its active principles. Evaporate the percolate on a water bath or in a vacuum still to not more than 800 mL, cool, add 200 mL of alcohol and, if necessary, add sufficient water to make the product measure 1000 mL. Mix.
Packaging and storage— Preserve in tight, light-resistant containers, and avoid exposure to direct sunlight and to excessive heat.
Alcohol content, Method I 611: between 18.0% and 20.0% of C2H5OH.
Residual solvents 467: meets the requirements.
(Official January 1, 2007)
Auxiliary Information— Staff Liaison : Maged H. Sharaf, Ph.D., Senior Scientist
Expert Committee : (DSB05) Dietary Supplements - Botanicals
USP29–NF24 Page 398
Phone Number : 1-301-816-8318