U.S. PHARMACOPEIA

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Labetalol Hydrochloride: White to off-white powder. Melts at about 180, with decomposition. Soluble in water and in alcohol; insoluble in ether and in chloroform.
Lactic Acid: Colorless or yellowish, practically odorless, syrupy liquid. Is hygroscopic. When it is concentrated by boiling, lactic acid lactate is formed. Specific gravity is about 1.20. Miscible with water, with alcohol, and with ether. Insoluble in chloroform. NF category: Buffering agent.
Lactitol: A white or light brown, odorless crystal. Has a mild, sweet taste, and no aftertaste. NF category: Flavors and perfumes; tablet and/or capsule diluent.
Anhydrous Lactose: White or almost white powder. Freely soluble in water; practically insoluble in alcohol. NF category: Tablet and/or capsule diluent.
Lactose Monohydrate: White, free-flowing powder. Freely but slowly soluble in water; practically insoluble in alcohol. NF category: Tablet and/or capsule diluent.
Lactulose Concentrate: Colorless to amber syrupy liquid, which may exhibit some precipitation and darkening upon standing. Miscible with water.
Lamivudine: White to off-white solid. Soluble in water. Melts at about 176.
Lanolin: Yellow, tenacious, unctuous mass, having a slight, characteristic odor. Insoluble in water, but mixes without separation with about twice its weight of water. Sparingly soluble in cold alcohol; more soluble in hot alcohol; freely soluble in ether and in chloroform. NF category: Ointment base.
Lanolin Alcohols: Hard, waxy, amber solid, having a characteristic odor. Insoluble in water; slightly soluble in alcohol; freely soluble in chloroform, in ether, and in petroleum ether. NF category: Emulsifying and/or solubilizing agent.
Lansoprazole: White to brownish-white powder. Freely soluble in dimethylformamide; practically insoluble in water. Melts at about 166, with decomposition.
Lecithin: The consistency of both natural grades and refined grades of lecithin may vary from plastic to fluid, depending upon free fatty acid and oil content, and upon the presence or absence of other diluents. Its color varies from light yellow to brown, depending on the source, on crop variations, and on whether it is bleached or unbleached. Is odorless or has a characteristic, slight nut-like odor and a bland taste. Partially soluble in water, but it readily hydrates to form emulsions. The oil-free phosphatides are soluble in fatty acids, but are practically insoluble in fixed oils. When all phosphatide fractions are present, lecithin is partially soluble in alcohol and practically insoluble in acetone. NF category: Emulsifying and/or solubilizing agent.
Letrozole: White to yellowish, crystalline powder. Freely soluble in dichloromethane; slightly soluble in alcohol; practically insoluble in water.
Leucine: White, practically odorless, tasteless crystals. Sparingly soluble in water; insoluble in ether.
Leucovorin Calcium: Yellowish-white or yellow, odorless powder. Very soluble in water; practically insoluble in alcohol.
Leucovorin Calcium Injection: Clear, yellowish solution.
Levamisole Hydrochloride: White or almost white, crystalline powder. Freely soluble in water; soluble in alcohol; slightly soluble in methylene chloride; practically insoluble in ether.
Levmetamfetamine: Clear, practically colorless liquid.
Levobunolol Hydrochloride: White crystalline, odorless powder. Soluble in water and in methanol; slightly soluble in alcohol and in chloroform.
Levocarnitine: White crystals or crystalline powder. Hygroscopic. Freely soluble in water, and in hot alcohol. Practically insoluble in acetone, in ether, and in benzene.
Levodopa: White to off-white, odorless, crystalline powder. In the presence of moisture, is rapidly oxidized by atmospheric oxygen and darkens. Slightly soluble in water; freely soluble in 3 N hydrochloric acid; insoluble in alcohol.
Levonordefrin: White to buff-colored, odorless, crystalline solid. Melts at about 210. Practically insoluble in water; freely soluble in aqueous solutions of mineral acids; slightly soluble in acetone, in chloroform, in alcohol, and in ether.
Levonorgestrel: White or practically white, odorless powder. Practically insoluble in water; soluble in chloroform; slightly soluble in alcohol.
Levorphanol Tartrate: Practically white, odorless, crystalline powder. Sparingly soluble in water; slightly soluble in alcohol; insoluble in chloroform and in ether. Melts, in a sealed tube, at about 110, with decomposition.
Levothyroxine Sodium: Light yellow to buff-colored, odorless, tasteless, hygroscopic powder. Is stable in dry air but may assume a slight pink color upon exposure to light. The pH of a saturated solution is about 8.9. Very slightly soluble in water; soluble in solutions of alkali hydroxides and in hot solutions of alkali carbonates; slightly soluble in alcohol; insoluble in acetone, in chloroform, and in ether.
Lidocaine: White or slightly yellow, crystalline powder. Has a characteristic odor and is stable in air. Practically insoluble in water; very soluble in alcohol and in chloroform; freely soluble in benzene and in ether. Dissolves in oils.
Lidocaine Hydrochloride: White, odorless, crystalline powder, having a slightly bitter taste. Very soluble in water and in alcohol; soluble in chloroform; insoluble in ether.
Lime: Hard, white or grayish-white masses or granules, or white or grayish white powder. Is odorless. Slightly soluble in water; very slightly soluble in boiling water.
Lincomycin Hydrochloride: White or practically white, crystalline powder. Is odorless or has a faint odor. Is stable in the presence of air and light. Its solutions are acid and dextrorotatory. Freely soluble in water; soluble in dimethylformamide; very slightly soluble in acetone.
Lincomycin Hydrochloride Injection: Clear, colorless to slightly yellow solution, having a slight odor.
Lincomycin Hydrochloride Soluble Powder: White to off-white, or light tan free-flowing, fine powder.
Lindane: White, crystalline powder, having a slight, musty odor. Practically insoluble in water; freely soluble in chloroform; soluble in dehydrated alcohol; sparingly soluble in ether; slightly soluble in ethylene glycol.
Linoleoyl Polyoxylglycerides: Amber, oily liquids. May develop deposit after prolonged storage periods at 20. Freely soluble in methylene chloride; practically insoluble but dispersible in water. NF category: Ointment base; solvent.
Liothyronine Sodium: Light tan, odorless, crystalline powder. Very slightly soluble in water; slightly soluble in alcohol; practically insoluble in most other organic solvents.
Lisinopril: White, crystalline powder. Melts at about 160, with decomposition. Soluble in water; sparingly soluble in methanol; practically insoluble in alcohol, in acetone, in acetonitrile, and in chloroform.
Lithium Carbonate: White, granular, odorless powder. Sparingly soluble in water; very slightly soluble in alcohol. Dissolves, with effervescence, in dilute mineral acids.
Lithium Citrate: White, odorless, deliquescent powder or granules, having a cooling, faintly alkaline taste. Freely soluble in water; slightly soluble in alcohol.
Loperamide Hydrochloride: White to slightly yellow powder. Melts at about 225, with some decomposition. Freely soluble in methanol, in isopropyl alcohol, and in chloroform; slightly soluble in water and in dilute acids.
Loratadine: White to off-white powder. Freely soluble in acetone, in chloroform, in methanol, and in toluene; insoluble in water.
Lorazepam: White or practically white, practically odorless powder. Insoluble in water; sparingly soluble in alcohol; slightly soluble in chloroform.
Losartan Potassium: White to off-white powder. Freely soluble in water; soluble in isopropyl alcohol; slightly soluble in acetonitrile.
Lovastatin: White to off-white, crystalline powder. Freely soluble in chloroform; soluble in acetone, in acetonitrile, and in methanol; sparingly soluble in alcohol; practically insoluble in hexane; insoluble in water.
Loxapine Succinate: White to yellowish, crystalline powder. Is odorless.
Lutein: Red, crystalline powder. Soluble in ethanol, in ethyl acetate, and in methylene chloride; partially soluble in hexane.
Lysine Acetate: White, odorless crystals or crystalline powder, having an acid taste. Freely soluble in water.
Lysine Hydrochloride: White, odorless powder. Freely soluble in water.