USP Ibuprofen RS—
Do not dry. Keep container tightly closed.
USP Idarubicin Hydrochloride RS—
Do not dry before using. Keep container tightly closed. Store in a freezer.
USP Idoxuridine RS—
Do not dry before using. Keep container tightly closed. Protect from light.
USP Ifosfamide RS—
Do not dry; determine the water content titrimetrically when used for quantitative analysis. Keep container tightly closed. Store at a temperature not exceeding 25

.
USP Imidazole RS—
Do not dry before using. Keep container tightly closed. Protect from light.
USP Imidurea RS—
Dry portion in vacuum over phosphorus pentoxide for 48 hours before using. Keep container tightly closed. Store in a desiccator.
USP Iminodibenzyl RS
(C
14H
13N

195.28)
—Dry portion over silica gel for 4 hours before using. Keep container tightly closed and protected from light.
USP Imipenem Monohydrate RS—
Do not dry before using. Keep container tightly closed. Store in a freezer.
USP Imipramine Hydrochloride RS—
Dry portion at 105

for 2 hours before using. Keep container tightly closed.
USP Inamrinone RS—
Do not dry before using; determine the water content titrimetrically at the time of use. Keep container tightly closed.
USP Inamrinone Related Compound A RS
[5-carboxamide[3,4
¢-bipyridin]-6(1
H)-one
]
(C
11H
9N
3O
2

215.21)
—Do not dry; use as is. Keep container tightly closed and protected from light.
USP Inamrinone Related Compound B RS
[N-(1,6-dihydro-6-oxo-(3,4
¢-bipyridine)-5-yl)-2-hydroxypropanamide
]
(C
13H
13N
3O
3

259.3)
—Do not dry; use as is.
USP Inamrinone Related Compound C RS
[1,6-dihydro-6-oxo-(3,4
¢-bipyridine)-5-carbonitrile
]
(C
11H
7N
3O

197.20)
—Do not dry; use as is.
USP Indapamide RS—
Dry portion at 105

for 4 hours before using. Keep container tightly closed. Protect from light. Store in a desiccator.
USP Indigotindisulfonate Sodium RS—
Dry portion at 105

for 3 hours before using. Keep container tightly closed. Protect from light. This material is hygroscopic.
USP Indinavir RS—
Do not dry. This is the monohydrate form of indinavir. Keep container tightly closed.
Change to read:
USP Indinavir
USP29 System Suitability RS
—

Do not dry. Keep container tightly closed.
USP29
USP Indocyanine Green RS—
Dry portion in vacuum at 50

for 3 hours before using. Keep container tightly closed.
USP Indomethacin RS—
Dry portion at a pressure below 5 mm of mercury at 100

for 2 hours before using. Keep container tightly closed. Protect from light.
USP Insulin RS—
Preserve at a temperature not exceeding

15

. After opening the vial, without delay, transfer the entire contents of the vial in accurately weighed portions to clean, dry volumetric flasks. Keep the flasks tightly closed, and store in a freezer. Do not dry before use for tests and assays.
USP Insulin (Beef) RS—
Do not dry. Store in a freezer at

20

to

18

; after opening, store in a tight container protected from air and humidity.
USP Insulin Human RS—
Preserve in a freezer at

20

to

18

, and, after opening the vial, store in a tight container. After opening the vial, without delay, transfer accurately weighed portions to clean, dry volumetric flasks. Keep the flasks tightly closed, and store in a freezer. Do not dry before use for tests and assays.
USP Insulin (Pork) RS—
Do not dry. Store in a freezer at

20

to

18

; after opening, store in a tight container protected from air and humidity.
USP Insulin Lispro RS.
USP Iodipamide RS—
Dry portion at 105

for 4 hours before using. Keep container tightly closed.
USP Iodixanol RS—
Dry portion at 105

for 4 hours before using. Keep container tightly closed, protected from light, and store in a dry place, preferably in a desiccator.
USP Iodixanol Related Compound A RS
[5-amino-N,N¢-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide].
USP Iodixanol Related Compound C RS
[5-[acetyl[3-[[3,5-bis[[(2,3-dihydroxypropyl)amino]carbonyl]-2,4,6-triiodophenyl]amino]-2-hydroxypropyl]amino]N,N¢-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide].
USP Iodixanol Related Compound D RS
[5-[acetyl(2-hydroxy-3-methoxypropyl)amino]-N,N¢-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide].
USP Iodixanol Related Compound E RS
[5-[[3-[[3-[[(2,3-dihydroxypropyl)amino]carbonyl]-5-[[amino]carbonyl]-2,4,6-triiodophenyl](acetylimino)]-2-hydroxypropyl]-(acetylimino)]-N,N¢-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide].
USP o-Iodohippuric Acid RS
(C
9H
8INO
3

305.07)
—Do not dry before using. Keep container tightly closed, and store in a desiccator. Protect from light.
USP Iodoquinol RS—
Do not dry. Keep container tightly closed.
USP Iohexol RS—
Do not dry before using. Keep container tightly closed. Protect from light.
USP Iohexol Related Compound A RS
[5-(acetylamino)-N,N¢-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide]
—Do not dry. Keep container tightly closed. Protect from light.
USP Iohexol Related Compound B RS
[5-amino-N,N¢-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-1,3-benzenedicarboxamide]
—Do not dry. Keep container tightly closed and protected from light.
USP Iohexol Related Compound C RS
[N,N¢-bis(2,3-dihydroxypropyl)-5-nitro-1,3-benzenedicarboxamide]
—Do not dry. Keep container tightly closed and protected from light.
USP Iopamidol RS—
Dry portion at 105

for 4 hours before using. Keep container tightly closed. Protect from light.
USP Iopamidol Related Compound A RS
[N,
N¢-bis-(1,3-dihydroxy-2-propyl)-5-amino-2,4,6-triiodoisophthalamide
]
(C
14H
18I
3N
3O
6

705.03)
—Do not dry before using. Keep container tightly closed and protected from light.
USP Iopamidol Related Compound B RS
[5-glycolamido-
N,
N¢-bis[2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-triiodoisophthalamide
]
(C
16H
20I
3N
3O
7

747.07)
—Do not dry. Keep container tightly closed, protected from light, at room temperature.
USP Iopromide RS
—Do not dry. For quantitative applications, use a value of 0.979 mg iopromide per mg on as-is basis. Keep container tightly closed. Protect from light.
USP Iopromide Related Compound A RS—
Do not dry. Keep container tightly closed and protected from light.
USP Iopromide Related Compound B RS
[5-(acetylamino)-N,N¢-bis(2,3-dihydroxypropyl)-2,4,6-triiodo-N-methyl-1,3-benzenedicarboxamide]—Do not dry. Keep container tightly closed.
USP Iothalamic Acid RS—
Dry portion at 105

for 4 hours before using. Keep container tightly closed.
USP Ioversol RS.
USP Ioversol Related Compound A RS—
Do not dry before using. Keep container tightly closed and protected from light.
USP Ioversol Related Compound B RS—
Do not dry before using. Keep container tightly closed and protected from light.
USP Ioxaglic Acid RS.
USP Ioxilan RS—
Do not dry. For quantitative applications, determine the water content titrimetrically at the time of use. Keep container tightly closed. Protect from light.
USP Ioxilan Related Compound A RS
[5-amino-2,4,6-triiodo-3
N-(2-hydroxyethyl)carbamoyl benzoic acid
]
(C
10H
9I
3N
2O
4

601.90)
—Dry at 105

for 2 hours before using. Keep container tightly closed. Protect from light.
USP Ipodate Sodium RS—
Dry portion in vacuum at 60

for 3 hours before using. Keep container tightly closed.
USP Irbesartan RS—
Do not dry.
USP Irbesartan Related Compound A RS
[1-pentanoylamino-cyclopentanecarboxylic acid [2'-(
1H-tetrazol-5-yl)-byphenyl-4-ylmethyl]-amide
]
(C
25H
30N
6O
2

446.54).
USP Isoetharine Hydrochloride RS—
Dry portion at 100

for 4 hours before using.
USP Isoflupredone Acetate RS—
Dry a portion at 105

for 4 hours before using. Keep container tightly closed. Protect from light.
USP Isoflurane RS—
Do not dry before using. Keep container tightly closed. Protect from light.
USP Isoflurane Related Compound A RS
[1-chloro-2,2,2-trifluoroethylchlorodifluoromethyl ether
]
(C
3HCl
2F
5O

219.49)
.
USP Isoflurane Related Compound B RS
[2,2,2-trifluoroethyldifluoromethyl ether
]
(C
3H
3F
5O

150.05)
—Do not dry before using. Keep container tightly closed. Protect from light.
[Caution—Extremely volatile liquid. Cool contents before opening ampul.
]
USP L-Isoleucine RS—
Dry portion at 105

for 3 hours before using. Keep container tightly closed.
USP Isomalathion RS
(C
10H
19O
6PS
2

330.37)
—Do not dry. Keep container tightly closed, and store in a cool place.
USP Isometheptene Mucate RS.
USP Isoniazid RS—
Dry portion at 105

for 4 hours before using. Keep container tightly closed. Protect from light.
USP Isopropamide Iodide RS—
Dry portion in vacuum at 60

for 2 hours before using. Keep container tightly closed. Protect from light.
USP Isopropyl Myristate RS—
Do not dry before using. After opening ampul, transfer contents to a tightly closed container, and protect from light.
USP Isopropyl Palmitate RS—
Do not dry before using. After opening ampul, transfer contents to a tightly closed container. Protect from light.
USP Isoproterenol Hydrochloride RS—
Dry portion in vacuum over phosphorus pentoxide for 4 hours before using. Keep the container tightly closed and protected from light.
Add the following:
USP Isomalt RS.
USP29
USP Isosorbide RS—
For quantitative applications, determine the water content titrimetrically. After opening the ampul, store in a tightly closed container.
USP Diluted Isosorbide Dinitrate RS—
[Caution—Undiluted material is explosive by percussion or excessive heat.
] This is a mixture containing 25% of isosorbide dinitrate in mannitol. Do not dry before using. Keep container tightly closed. Prevent exposure to excessive heat.
USP Isosorbide Mononitrate RS.
USP Isosorbide Mononitrate Related Compound A RS
[1,4:3,5-dianhydro-
D-glucitol 2-nitrate
]
(C
6H
9NO
6

191.14).
USP Isotretinoin RS—
Do not dry. Store vials at a temperature below 0

; allow to reach room temperature before opening, and use the contents promptly after opening vials. Protect from air and light once vial has been opened.
USP Isoxsuprine Hydrochloride RS—
Dry portion at 105

for 1 hour before using. Keep container tightly closed.
USP Isradipine RS—
Dry portion at 105

for 4 hours before using. Keep container tightly closed and protected from light.
USP Isradipine Related Compound A RS
[isopropyl methyl 4-(4-benzofurazanyl)-2,6-dimethyl-3,5-pyridinedicarboxylate
]
(C
19H
19 N
3O
5

369.38)
—Do not dry. Keep container tightly closed, protected from light, and store in a freezer.
USP Ivermectin RS—
Do not dry. Protect from light. Keep container tightly closed.